NWO grants collaborative cryo-microscopy development with ImPhys
A cryogenic three-beams microscope to track and isolate proteins for near-atomic resolution electron cryo-microscopy
Spearheaded by our colleague Jacob Hoogenboom at the Department of Imaging Physics (ImPhys), a research team comprising Jacob’s group and us, together with industry partners Delmic and Demcon-Kryoz will develop a novel cryogenic microscope (CRYO3BEAMS) in which a high-resolution light microscope is integrated with focused electron and ion beam systems to allow targeted extraction of specific proteins for high-resolution structural determination. The project builds on Jacob’s prior development of the SECOM platform now marketed by Delmic. See here for more information.