Our 300 kV JEM-3200FSC cryo-EM instrument at BN!
Our 300 kV JEM-3200FSC cryo-EM instrument at BN!

I am a group leader at the Department of Bionanoscience and part of the Electron Nanoscopy group at the Kavli Institute in Delft.

I studied molecular sciences at Leiden University and the University of Erlangen, initially focussing on the application of computational quantum chemistry methods to structure-based drug design. An interest in protein structure made me move into experimental biophysics and I obtained my PhD in structural biology at the Bijvoet Center for Biomolecular Research in Utrecht. I then joined the European Molecular Biology Laboratory (EMBL), where I have combined X-ray crystallography and electron cryo-microscopy (cryo-EM) to study large molecular assemblies involved in selective autophagy. I am also interested in the technical challenges for image processing and sample preparation in cryo-EM and XFEL imaging, and I develop computational methods with the aim to make the interpretation of high-resolution cryo-EM maps a more routine task.

In my free time I enjoy sports, art and nature and I like to be outdoors. I am also still trying to locate the best cup of coffee in Delft.

ORCID iD iconorcid.org/0000-0002-7761-2027